DNA is made of four bases – A (adenine), T (thymine), C (cytosine) and G (guanine). Or is it? Researchers at Freie Universität Berlin have created an artificial base and directed the evolution of a bacterium to generate an organism that uses the new base, 5-chlorouracil, instead of thymine.
synthetic cell archive.
Following from the creation of the artificial cell in 2010 using a synthetic copy of a genome found in nature, US researchers have made another significant step forward. they have created synthetic proteins based on genetic sequences that do not occur in nature. These proteins have been able to sustain life in bacteria, and the results are published in PLoS ONE.
The Genome Engineering blog launched in May 2010, and to celebrate the New Year, we bring you the top ten posts of 2010.
Following on from the development of the self-replicating synthetic bacterial cell, researchers at the J Craig Venter Institute (JCVI) have created a synthetic mouse mitochondrial genome.
BIOFAB, set up by bioengineers from the University of California, Berkeley, and Stanford University to create standard DNA sequences or ‘parts’ for researchers, expects to have its first sequences available by the end of 2010.
Established in December 2009, BIOFAB (International Open Facility Advancing Biotechnology) aims to characterise microbial control …
J Craig Venter and colleagues at the J Craig Venter Institute have created the first self-replicating, synthetic bacterial cell, based on a synthetic genome transplanted into a host bacterial cell
