NextBio has launched NextBio Clinical, extending its existing life sciences platform to translational medicine applications such as biomarker discovery and clinical trial optimization by adding in curated genomic, molecular and clinical profiles from thousands of individual patients to the platform’s existing repository of data from animal and cell line models.
sequencing archive.
We’re used to reading about targeted therapies and the promise of personalised medicine through the application of genomic technologies; this has been something of a hot topic for a number of years and pharmaceutical companies have long since implemented collection of biological samples as standard practice in their clinical trials to facilitate genomic research.
Hints and tips from Nucleic Acids Research: Ultrasensitive detection of rare mutations using next-generation targeted resequencing.
Hints and tips from Nucleic Acids Research: Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform.
Researchers from Amsterdam have sequenced the genome of a woman who lived to 115, to assess the effect of her genes on her long and healthy life.
Deltaproteobacteria are aerobic and anaerobic Gram-negative bacteria. A team of researchers from the UK and USA, including the J Craig Venter Institute, the University of California at San Diego, and Illumina Cambridge, have used single-cell genome amplification, sequencing, and assembly techniques to assemble a genome from a single, uncultured cell.
Startup Medicinal Genomics has sequenced the genome of Cannabis sativa and Cannabis indica (marijuana), with 131 billion bases of sequence, for around $200,000. The sequence is still a draft and has been posted on Amazon’s EC2 public cloud computing service, but has not yet been published in peer-reviewed journals. The data is expected to be available towards the end of 2011, and the company aims to develop therapeutics that maximise its medicinal activity and minimise the psychoactive effects.
In a few years’ time, having your genome sequenced might become a routine medical procedure. New parents will probably even know the complete genetic code of their kids a few minutes after their birth. The technology behind full-genome sequencing is indeed growing unexpectedly fast, leading way to a complete revolution.
Ion Torrent, a Connecticut-based start-up, is bringing the cost of genome sequencing down again with its desktop sequencing machine, the Ion Personal Genome Machine.
The next plant in line for the whole genome sequencing treatment is set to be the lupin. This will be the first major plant genome sequencing project in Australia, and is a collaboration between the Centre for Food and Genomic Medicine and the Commonwealth Scientific and Research Organization (CSIRO).
The A$1.5 …
